Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 39: 30-36, 1975;
8750-7587/75 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shaw, W. A.
Right arrow Articles by Issekutz, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shaw, W. A.
Right arrow Articles by Issekutz, B., Jr

Journal of Applied Physiology, Vol 39, Issue 1 30-36, Copyright © 1975 by American Physiological Society

ARTICLES

Interrelationship of FFA and glycerol turnovers in resting and exercising dogs

W. A. Shaw, T. B. Issekutz and B. Issekutz Jr

Dogs with indwelling arterial and venous catheters ran on a treadmill on a 10% or on a 15% slope at 100 m/min. Glycerol turnover ([2-3H]-glycerol) and FFA turnover ([1-14C]palmitate) were measured simultaneously. Both turnovers were greatly increased by exercise. Similar increases were produced in resting dogs by norepinephrine infusions (0.5 mug/kg-min). At rest, as well as during exercise, there was a straight-line correlation between the ratio of disappearance of each substrate and their respective plasma concentrations. Over a wide range there was a straight-line correlation between the rate of production of FFA (RaFFA) and that of glycerol (RaGLY) at rest as well as during exercise. At any given RaFFA, RaGLY was higher in the running than in the resting dog. At rest the ratio of RaFFA/RaGLY was found to give the theoretical value of 3.0 only when RaFFA was 10-15 mumol/kg-min, below this the ratio was lower and above this it was higher. During exercise the ratio was lower than at rest and at heavier load lower than at lighter work. The results suggest that in vivo a combination of partial and complete lipolysis as well as reesterification occurs. The glucose equivalent of the glycerol turnover (if 100% converted) represents (under the given experimental conditions) 14-18% of the hepatic glucose output on the 15% slope and 20-25% of it on the 10% slope.


This article has been cited by other articles:


Home page
 J. Exp. Biol.Home page
E. Vaillancourt and J.-M. Weber
Lipid mobilization of long-distance migrant birds in vivo: the high lipolytic rate of ruff sandpipers is not stimulated during shivering
J. Exp. Biol., April 1, 2007; 210(7): 1161 - 1169.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
J. Weber and T O'Connor
Energy metabolism of the Virginia opossum during fasting and exercise
J. Exp. Biol., January 4, 2000; 203(8): 1365 - 1371.
[Abstract] [PDF]

Home page
 J. Exp. Biol.Home page
S. Bernard, S. Reidy, G Zwingelstein, and J Weber
Glycerol and fatty acid kinetics in rainbow trout: effects of endurance swimming
J. Exp. Biol., January 2, 1999; 202(3): 279 - 288.
[Abstract] [PDF]

Home page
 J. Appl. Physiol.Home page
T. J. Horton, M. J. Pagliassotti, K. Hobbs, and J. O. Hill
Fuel metabolism in men and women during and after long-duration exercise
J Appl Physiol, November 1, 1998; 85(5): 1823 - 1832.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
R. L. Judd, R. Nelson, S. Klein, M. D. Jensen, and J. M. Miles
Measurement of plasma glycerol specific activity by high performance liquid chromatography to determine glycerol flux
J. Lipid Res., May 1, 1998; 39(5): 1106 - 1110.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online