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J Appl Physiol 38: 358-359, 1975;
8750-7587/75 $5.00
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Journal of Applied Physiology, Vol 38, Issue 2 358-359, Copyright © 1975 by American Physiological Society

ARTICLES

Permanent cannulation of the hepatic portal vein in rats

R. Sable-Amplis and D. Abadie

A technique is described for chronic cannulation of the hepatic portal vein in rats. The T-shaped cannula is made in the laboratory from polyethylene tubing. Implantation of the cannula allows injection or blood withdrawal in a small laboratory animal which is unanesthetized and unrestrained. Simultaneous implantation of intracardotid and intraportal cannulas permits comparisons of blood composition in order to study the role of the liver or intestinal absorption.




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