Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 38: 228-235, 1975;
8750-7587/75 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Demedts, M.
Right arrow Articles by van de Woestijne, K. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Demedts, M.
Right arrow Articles by van de Woestijne, K. P.

Journal of Applied Physiology, Vol 38, Issue 2 228-235, Copyright © 1975 by American Physiological Society

ARTICLES

Inflection point on transpulmonary pressure-volume curves and closing volume

M. Demedts, J. Clement, D. C. Stanescu and K. P. van de Woestijne

In 20 healthy subjects and 18 patients with bronchial obstruction, closing volume (CV) on single-breath nitrogen washout curves and inflection point (IP) on transpulmonary pressure-volume curves were recorded simultaneously during slow expiratory vital capacity maneuvers. IP and CV did not occur at identical lung volumes, IP being systematically larger than CV for small CV values. This discrepancy could not be attributed to an esophageal or mediastinal artifact. It is suggested that, though CV and IP both express "airway closure," their sensitivity to closure may differ: CV underestimates closure because of a dead space effect; the latter may vary individually. On the other hand, IP may not reflect the true beginning of closure, particularly when it occurs at higher lung volumes.


This article has been cited by other articles:


Home page
 Br J AnaesthHome page
G. B. Drummond and J. Milic-Emili
Forty years of closing volume
Br. J. Anaesth., December 1, 2007; 99(6): 772 - 774.
[Full Text] [PDF]

Home page
 ChestHome page
K. M. Creamer, L. L. McCloud, L. E. Fisher, and I. C. Ehrhart
Pentoxifylline Rescue Preserves Lung Function in Isolated Canine Lungs Injured With Phorbol Myristate Acetate
Chest, June 1, 2001; 119(6): 1893 - 1900.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
K. M. CREAMER, L. L. MCCLOUD, L. E. FISHER, and I. C. EHRHART
Ventilation above Closing Volume Reduces Pulmonary Vascular Resistance Hysteresis
Am. J. Respir. Crit. Care Med., October 1, 1998; 158(4): 1114 - 1119.
[Abstract] [Full Text] [PDF]

Home page
 J Intensive Care MedHome page
T. F. Morley
Capnography in the Intensive Care Unit
J Intensive Care Med, September 1, 1990; 5(5): 209 - 223.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online