Journal of Applied Physiology Journal of Applied Physiology
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J Appl Physiol 20: 782-784, 1965;
8750-7587/65 $5.00
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A comparison of two methods for evaluating surface properties of the lung

W. F. Howatt 1 and L. B. Strang 1

1 Department of Paediatrics, University College Hospital Medical School, and Department of Pharmacology, University College, London, England

Indices of the surface tension properties of fetal lamb lungs were obtained by the bubble stability method and from direct measurements of a lung extract on a Langmuir-Wilhelmy balance. A comparison of 102 determinations by each method on 31 fetal lamb lungs gave a statistically significant positive correlation coefficient. A comparison of the surface balance index with a pressure-volume deflation index and with gestation and of the bubble stability index with gestation gave statistically significant positive correlation coefficients. Storage by freezing for 21–112 days did not alter either index of surface tension.

lung surface tension; measurement of lung surface tension; surface balance; lung bubbles

Submitted on October 15, 1964






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