Journal of Applied Physiology
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J Appl Physiol 20: 691-695, 1965;
8750-7587/65 $5.00
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Instantaneous blood flow in the human aorta

Robert E. Snell 1, James M. Clements 1, Dali J. Patel 1, Donald L. Fry 1, and Peter C. Luchsinger 1

1 Cardiopulmonary Physiology Research Laboratory, Veterans Administration Hospital, and Department of Medicine, Georgetown University School of Medicine, Washington, D.C., and Section on Clinical Biophysics, Cardiology Branch, National Heart Institute, National Institutes of Health, Bethesda, Maryland

The computed pressure-gradient technique has been applied to the measurement of instantaneous aortic blood flow in 15 male subjects. The mean values of those curves obtained in the ascending aorta were compared with simultaneous measurements made by the dye-dilution technique. The correlation coefficient between the two methods was 0.85 and the slope of the regression line 0.80. The ability to measure flow by the pressure-gradient technique depends mainly on the accuracy of the catheter-manometer system, radius measurement, and the estimation of "zero flow."

pressure-gradient technique; methods of blood flow measurement

Submitted on June 22, 1964






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