Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 20: 653-663, 1965;
8750-7587/65 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Macklem, P. T.
Right arrow Articles by Wilson, N. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Macklem, P. T.
Right arrow Articles by Wilson, N. J.

Measurement of intrabronchial pressure in man

Peter T. Macklem 1 and N. J. Wilson 1

1 Joint Cardio-respiratory Service, Royal Victoria Hospital, Montreal, Quebec, Canada

By measuring total and lateral airway pressures in intact normal man, simultaneously with esophageal pressure, volume, and flow, it was possible to estimate the pressure difference across the wall of the airway, the pressure-flow curves of various segments of the airway, and the compliance of the airway. The results showed that: 1 Expiratory airway compression only occurs between the segmental bronchi and the glottis at volumes between 75 and 25% VC. 2) Expiratory flow is limited by compression of these airways. 3) The resistance of airways between segmental bronchi and trachea is variable, being markedly affected both by lung volume and pleural pressure. Tracheal resistance varies little with lung volume, but considerably with pleural pressure. The resistance of the airways between alveoli and segmental bronchi varies with lung volume but little with pleural pressure. These are probably the major resistance airways during quiet breathing. 4) Airway compliance is inversely related to lung volume. 5) The Bernouilli effect is large in large airways and helps to limit expiratory flow.

bronchial pressure; airway resistance; airway compliance; maximal expiratory flow; equal pressure point; lung mechanics; airway compression

Submitted on November 5, 1964




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
A. Hoffman, H. Kuehn, K. Riedelberger, R. Kupcinskas, and M. B. Miskovic
Flowmetric comparison of respiratory inductance plethysmography and pneumotachography in horses
J Appl Physiol, December 1, 2001; 91(6): 2767 - 2775.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
H. J. L. BRACKEL, O. F. PEDERSEN, P. G. H. MULDER, S. E. OVERBEEK, K. F. KERREBIJN, and J. M. BOGAARD
Central Airways Behave More Stiffly during Forced Expiration in Patients with Asthma
Am. J. Respir. Crit. Care Med., September 1, 2000; 162(3): 896 - 904.
[Abstract] [Full Text]

Home page
 Am. J. Respir. Crit. Care Med.Home page
P. T. MACKLEM
The Mechanics of Breathing
Am. J. Respir. Crit. Care Med., April 1, 1998; 157(4): S88 - S94.
[Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
O. F. Pedersen, H. J. L. Brackel, J. M. Bogaard, and K. F. Kerrebijn
Wave-speed-determined flow limitation at peak flow in normal and asthmatic subjects
J Appl Physiol, November 1, 1997; 83(5): 1721 - 1732.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online