Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 20: 488-490, 1965;
8750-7587/65 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lloyd, T. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lloyd, T. C., JR.

Pulmonary vasoconstriction during histotoxic hypoxia

Thomas C. Lloyd JR. 1

1 Department of Medicine, School of Medicine, Western Reserve University, Cleveland, Ohio

Increases in pulmonary vascular resistance could be produced in excised perfused ventilated dog lung lobes by lowering the alveolar Po2. When dinitrophenol was added to the perfusate a similar change in the vascular bed occurred that could be reversed by ventilating with supernormal oxygen concentrations. The similarity of the responses to dinitrophenol and lowered alveolar Po2 was demonstrated using normally and retrogradely perfused lobes. The hypoxic pressor response was shown to be independent of the Po2 of blood contained in the arteries and veins.

Note:
(With the Technical Assistance of Emily McCartney)

dinitrophenol; cyanide; vascular effect of intravascular oxygen concentration

Submitted on August 13, 1964




This article has been cited by other articles:


Home page
 Am. J. Respir. Cell Mol. Bio.Home page
N. Weissmann, N. Ebert, M. Ahrens, H. A. Ghofrani, R. T. Schermuly, J. Hanze, L. Fink, F. Rose, J. Conzen, W. Seeger, et al.
Effects of Mitochondrial Inhibitors and Uncouplers on Hypoxic Vasoconstriction in Rabbit Lungs
Am. J. Respir. Cell Mol. Biol., December 1, 2003; 29(6): 721 - 732.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
G. G. Konduri and J. Mattei
Role of oxidative phosphorylation and ATP release in mediating birth-related pulmonary vasodilation in fetal lambs
Am J Physiol Heart Circ Physiol, October 1, 2002; 283(4): H1600 - H1608.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
S. O Brij and A. J Peacock
Cellular responses to hypoxia in the pulmonary circulation
Thorax, December 1, 1998; 53(12): 1075 - 1079.
[Full Text]

Home page
 ScienceHome page
E. D. Robin, C. E. Cross, J. E. Millen, and H. V. Murdaugh Jr.
Humoral Agent from Calf Lung Producing Pulmonary Arterial Vasoconstriction
Science, May 12, 1967; 156(3776): 827 - 830.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online