Journal of Applied Physiology Add DOIs to your references at manuscript stage!
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 19: 901-906, 1964;
8750-7587/64 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hedley-Whyte, J.
Right arrow Articles by Laver, M. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hedley-Whyte, J.
Right arrow Articles by Laver, M. B.

O2 solubility in blood and temperature correction factors for Po2

J. Hedley-Whyte 1 and M. B. Laver 1

1 Anesthesia Laboratory of the Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts

Tonometry of 100 paired samples of blood and measurement of Po2 before and after warming in a sealed syringe showed that the relative solubility of O2 (agrB/agrHH2O) in fully saturated blood is constant at all temperatures between 24.5 and 38 C, i.e., fully saturated blood appears to behave as a dilute aqueous solution. When Po2 is kept constant during cooling the relative increase in dissolved O2 in blood is the same as with water. Thus, when cooling from 38 to 20 C the increase in dissolved O2, if Po2 is kept constant, is 31%. Correction factors for the effect of temperature on Po2 of blood warmed to 38 C can be based on ratios of agrHH2O38/agrHH2OT. These factors were found to give adequate correction at O2 tensions above 250 mm Hg. Inaccuracies were found when previously proposed factors were applied to blood having a Po2 of 300 mm Hg. These results were interpreted as showing that blood is essentially fully saturated at a Po2 of approximately 250 mm Hg.

Note:
(With the Technical Assistance of A. Murphy and A. Seifen)

relative solubility; agr; hypothermia; hemoglobin; dissociation; tonometry; O2 electrode; physiologic shunt

Submitted on December 23, 1963




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
M. E. Jessen, A. S. Abd-Elfattah, and A. S. Wechsler
Neonatal Myocardial Oxygen Consumption During Ventricular Fibrillation, Hypothermia, and Potassium Arrest
Ann. Thorac. Surg., January 1, 1996; 61(1): 82 - 87.
[Abstract] [Full Text]

Home page
 ANGIOLOGYHome page
R. Sarma, C. Prickett III, and J. L. Johnson
Assessment of Clinical Laboratory Techniques in the Measurement of Oxygen Saturation in Whole Blood
Angiology, September 1, 1976; 27(9): 502 - 508.
[Abstract] [PDF]

Home page
 Arch SurgHome page
N. M. GREENE
Tissue Oxygen Tension in the Anesthetized Patient
Arch Surg, February 1, 1966; 92(2): 164 - 177.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online