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J Appl Physiol 19: 157-158, 1964;
8750-7587/64 $5.00
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Continuous infusion in rats

A. L. Kennan 1

1 Department of Gynecology and Obstetrics, University of Wisconsin School of Medicine, Madison, Wisconsin

A simple method of continuous intravascular infusion is described that involves little trauma and is tolerated by pregnant rats. The mechanism is a polyethylene catheter in the tail vein, an accommodating cage in which the rat can move freely, and a mercury U tube to provide pressure for infusion. The method has several advantages in that extensive surgery is not required, the animal can be conditioned to the cage before placement of the catheter, infusion under pressure is possible, and the apparatus is simple and can be set up in any laboratory with equipment at hand.

pregnant rat; catheter; cage

Submitted on May 31, 1963






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