Journal of Applied Physiology Journal of Neurophysiology
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J Appl Physiol 18: 553-556, 1963;
8750-7587/63 $5.00
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Effect of a systemic A-V fistula and of pulmonary embolization on diffusing capacity

M. Henry Williams JR. 1 and Bruce J. Sobol 1

1 Cardiorespiratory Laboratory, Grasslands Hospital, Valhalla, New York

Opening an aortic-caval fistula in anesthetized dogs was associated with slight but significant increase of the steady-state diffusing capacity of the lungs. Extensive pulmonary embolization with glass beads resulted in a slight and insignificant fall of the diffusing capacity. Increased pulmonary blood flow and obstruction to pulmonary arterioles do not appear to be associated with marked increase and decrease of the diffusing capacity.

Submitted on October 5, 1962






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