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J Appl Physiol 16: 186-190, 1961;
8750-7587/61 $5.00
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An improved heart-lung preparation ventilated by negative pressure

William L. Sheehan 1, William B. Kinzie 1, Kenneth L. Westbrook 1, William A. Spencer 1, and Hebbel E. Hoff 1

1 Departments of Physiology and Rehabilitation, Baylor University College of Medicine, Houston, Texas

Five isolated canine heart-lung preparations were successfully ventilated with intermittent negative pressure in a specially constructed chamber. Improved cardiopulmonary dynamics resulted in increased survival time and improved performance of all preparations. Results obtained with these preparations exceed most of the others reported in the literature.

Submitted on May 9, 1960






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