Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 15: 1123-1129, 1960;
8750-7587/60 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Marx, T. I.
Right arrow Articles by Moeller, C. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Marx, T. I.
Right arrow Articles by Moeller, C. E.

Diffusion of oxygen into a film of whole blood

Thomas I. Marx 1, Warren E. Snyder 1, Andrew D. St. John 1, and Calvin E. Moeller 1

1 Midwest Research Institute, Kansas City, Missouri

In the study of artificial blood oxygenation, the mechanism of oxygen diffusion and absorption in a blood film is of particular interest. An equation was derived for the diffusion of oxygen into whole blood films that are thick compared to the red cell size. The equation, which was solved on an electronic analogue computer, showed that simple expressions for an advancing interface of oxygenated blood are good approximations. An equation for a blood film bounded by a semipermeable membrane was also derived. An experiment was conducted to confirm the advancing interface theory. In a second experiment, the diffusivity of oxygen in whole blood was found to be approximately 1.3 (10–5) cm2/sec. When using highly permeable membranes, such as silicone rubber, in a blood oxygenator, the relative permeabilities of a blood film and the membrane are such that in many cases the resistance of the blood film is the controlling factor.

Submitted on October 5, 1959






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online