Proteinuria during the 24-hour period following exercise

¹ Department of Pathology, University of Wisconsin Medical School, Madison, Wisconsin

The urine of 10 football players, collected for 24 hours following a practice game, was found to contain 2.3–15.2 times as much protein as urine collected following a period of rest. No changes were noted on electrophoresis of the serum proteins. The renal clearance of serum albumin increased more than the clearance of serum globulins following exercise, but in both the control and post-exercise specimens the clearance of globulins and percentage of globulins in the urine usually exceeded these values for albumin. Considerable variation in the excretion of proteins was noted among individual subjects in the control period; as protein excretion increased following exercise, the protein excretion patterns became more uniform in these subjects. Compared to the previously described exercise proteinuria which occurs immediately following exercise, this second phase is characterized by less intense protein excretion and longer duration.