Sweat iodide excretion in patients with cystic fibrosis of the pancreas

¹ Department of Pediatrics, University of Nebraska College of Medicine, Omaha, Nebraska

Thirteen children with cystic fibrosis of the pancreas and fourteen normal children were studied. After preliminary saturation of the thyroid with Lugol's solution, a tracer dose of I¹³¹ was administered. Sweating was encouraged with wool blankets and heating pads. The sweat was collected on gauze pads which were then centrifuged to provide the free fluid. Sweat chloride was determined as were the number of disintegrations per minute in 1 cc of both sweat and serum. It was reconfirmed that fibrocystics excrete more chloride in their sweat than do normals. It was further found that fibrocystics excrete more iodide in their sweat than do normals.