Journal of Applied Physiology
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J Appl Physiol 14: 781-784, 1959;
8750-7587/59 $5.00
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Transcapillary exchange rates in acute and intermittent hyperthermia

H. P. K. Agersborg JR. 1, George Barlow 1, and R. R. Overman 1

1 Institute of Clinical Investigation, University of Tennessee Medical Units, Memphis, Tennessee

The effects of severe, acute and mild, intermittent hyperthermia on the transcapillary exchange rates of Na24 and of K42 have been studied in dogs. Measurements were made before and after a single exposure to a rectal temperature of 42.5°C for 1 hour, before and after a single exposure to a rectal temperature of 41.5°C and before and after exposure to the seventh daily rectal temperature elevation to 41.5°C. The sodium exchange rate was seen to be altered in every instance in which a post-hyperthermic measurement was obtained. A measured change in the potassium exchange rate was found to exist only in the animals which had been exposed to daily bouts of intermittent hyperthermia for 7 days.

Submitted on February 10, 1959






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