Journal of Applied Physiology
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J Appl Physiol 14: 567-568, 1959;
8750-7587/59 $5.00
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Summation and tetanus in postmortem human heart muscle

William C. Ullrick 1, Eugene A. Lentini 1, and Sheldon C. Sommers 1

1 Departments of Physiology and Pathology, Boston University School of Medicine, Boston, Massachusetts

Induced isometric contractions were recorded from trabeculae carneae from the left ventricles of human hearts obtained at autopsy. Increasing the frequency of stimulation from a driving rate of 1/sec. up to 10/sec. resulted in complete tetanic contractions in the majority of experiments. The tetanic response was usually coupled with summation. The occurrence or nonoccurrence of tetanus was correlated with the contraction time-refractory period ratios.

Submitted on December 16, 1958






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