Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 13: 105-108, 1958;
8750-7587/58 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Repplinger, E.
Right arrow Articles by Tocantins, L. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Repplinger, E.
Right arrow Articles by Tocantins, L. M.

Species Characteristics of Platelets of X-Irradiated Mice Treated With Rat Bone Marrow

E. Repplinger 1, I. R. Schwartz 1, C. C. Congdon 1, and L. M. Tocantins 1

1 From the Charlotte Drake Cardeza Foundation, Jefferson Medical College, Philadelphia, Pennsylvania and Division of Biology, Oak Ridge National Laboratory, Oak Ridge, Tennessee

Transplantation of heterologous marrow causes survival of lethally irradiated mice by repopulating the bone marrow of the recipient with donor red and white cells. A study of the extent and duration of the ‘take’ of the transplanted platelet forming tissues was carried out by preparing antisera in rabbits against rat and mouse platelets and using these sera to identify platelets circulating in the mouse at intervals after transplantation of rat bone marrow. Rat platelets were evident in the blood of such mice 2–6 days after transplantation. In some animals, rat platelets were never preponderant; in others, after rat platelets were in the majority, reversion to mouse platelets took place. There was no apparent correlation between platelet species and length of survival. There was evidence of at least a partial ‘take’ of rat platelet precursors in every mouse, but the permanence of the ‘take’ was variable.

Submitted on December 19, 1957






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online