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J Appl Physiol 12: 445-447, 1958;
8750-7587/58 $5.00
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Estimation of Volume of a Circulatory Model by the Hamilton and the Bradley Methods at Varying Flow Volume Ratios

E. Braunwald 1, A. P. Fishman 1, and A. Cournand 1

1 From the Department of Medicine, Columbia University, College of Physicians and Surgeons and the Cardio-Pulmonary Laboratory (Columbia University Division), Bellevue Hospital, New York City

The accuracy of the Hamilton mean circulation time method and of the Bradley equilibration method for the measurement of the volume contained within a segment of the vascular bed were evaluated in an artificial circulatory model. The Hamilton method provided accurate volume measurements over the entire range of minute flow to volume ratios examined, i.e. from .37/1.0 to 7.75/1.0. However, accurate measurements with the Bradley method were possible only with minute flow to volume ratios below 4.0/1.0.

Submitted on May 6, 1957






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