Journal of Applied Physiology http://www.adinstruments.com/labchart/faseb
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 12: 413-424, 1958;
8750-7587/58 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bartlett, R. G.
Right arrow Articles by Specht, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bartlett, R. G., JR.
Right arrow Articles by Specht, H.

Oxygen Cost of Breathing

R. G. Bartlett JR. 1, H. F. Brubach 1, and H. Specht 1

1 From the Laboratory of Physical Biology, National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland

Three new procedures and apparatus for measuring the oxygen cost of breathing are described. Also presented are data on the O2 cost of breathing over the entire ventilatory range. It was observed that each breathing rate established a different O2 uptake-ventilation curve. An O2 uptake-ventilation curve produced by ‘optimum’ combinations of breathing rate and tidal volume (which are close to inherently chosen combinations) was shown to be composed of the ‘efficient’ segments of the O2 uptake-ventilation curves. As the maximum effort at any given breathing rate was approached the O2 cost per unit ventilation increased very rapidly producing a large range of O2 uptake values for subjectively equivalent ‘maximum’ efforts. It was therefore suggested that when used as a clinical test more uniform results could be expected if the breathing effort were less than maximum. A volume ‘deficit’ as a result of time ‘loss’ in flow reversal during the breathing cycle is introduced as a newly described factor affecting the work of breathing. It is shown that this factor results in increasing nonelastic work with increasing breathing rates at constant pulmonary ventilation. The opposite effect of increasing breathing rate on elastic and nonelastic work at constant pulmonary ventilation establishes an optimal breathing frequency for a given pulmonary ventilation. This optimal frequency may be determined from a family of O2 uptake-ventilation curves. It is also shown that this family of curves may be adjusted so as to also indicate the optimal breathing frequencies for various alveolar ventilations. An explanation is presented for the wide differences in previously reported O2 uptake-ventilation curves.

Submitted on October 9, 1957




This article has been cited by other articles:


Home page
 ptjournalHome page
A. Y. Jones, E. Dean, and C. C. Chow
Comparison of the Oxygen Cost of Breathing Exercises and Spontaneous Breathing in Patients With Stable Chronic Obstructive Pulmonary Disease
Physical Therapy, May 1, 2003; 83(5): 424 - 431.
[Abstract] [Full Text] [PDF]

Home page
 Am J Crit CareHome page
C. D. Epstein, N. El-Mokadem, and J. R. Peerless
Weaning Older Patients From Long-term Mechanical Ventilation: A Pilot Study
Am. J. Crit. Care., July 1, 2002; 11(4): 369 - 377.
[Abstract] [Full Text] [PDF]

Home page
 Arch SurgHome page
W. E. NEVILLE, A. SPINAZZOLA, L. P. SCICCHITANO, and H. D. LANGSTON
Tracheostomy and Assisted Ventilation: Use in Respiratory Insufficiency in the Postsurgical Patient
Arch Surg, July 1, 1964; 89(1): 149 - 158.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online