Journal of Applied Physiology
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J Appl Physiol 11: 390-404, 1957;
8750-7587/57 $5.00
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Dynamic Response Characteristics of Systems for Continuous Recording of Concentration Changes in a Flowing Liquid (for Example, Indicator-Dilution Curves)

Irwin J. Fox 1, William F. Sutterer 1, and Earl H. Wood 1

1 From the Section of Physiology, Mayo Clinic and Mayo Foundation, Rochester Minnesota

A technique for determining the dynamic response characteristics of cuvette oximeters, densitometers or other devices for recording concentration changes in a flowing liquid, such as indicator-dilution curves in flowing blood, has been described. The dynamic response of the systems studied improved when the rate of blood flow through the system was increased and when the internal diameter of the tubing (catheters) leading to the detecting element of the cuvette was decreased, while increasing the length of connecting tubing decreased this response. These factors are of much greater importance in determining the dynamic response of presently available oximeters and densitometers than are the electric components of these systems.

Submitted on February 11, 1957






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