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J Appl Physiol 11: 93-96, 1957;
8750-7587/57 $5.00
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Influence of Alterations in Arterial Blood pH and Carbon Dioxide Tension on Plasma Potassium Levels in Humans Anesthetized With Nitrous Oxide, Thiopental and Succinyldicholine

Byron D. Petersen 1, J. Albert Jackson 1, Joseph J. Buckley 1, and Frederick H. Van Bergen 1

1 From the Department of Anesthesiology, University of Minnesota College of Medicine, Minneapolis, Minnesota

Plasma K+ levels were followed during states of normocapnea, hypercapnea, hypocapnea and the ‘blow-off’ period immediately following hypercapnea. Plasma potassium remained unaltered during normocapnea and hypercapnea. A statistically significant decrease in plasma potassium was noted in hypocapnea. A tendency for plasma potassium to rise during the posthypercapneic period was observed. No significant electrocardiographic changes were noted. Possible explanations of these findings are discussed.

Submitted on February 6, 1957






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