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J Appl Physiol 103: 1894-1899, 2007. First published June 7, 2007; doi:10.1152/japplphysiol.00464.2007
8750-7587/07 $8.00
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INVITED REVIEW

HIGHLIGHTED TOPIC
Perspectives in Innate and Acquired Cardioprotection

Perspectives in innate and acquired cardioprotection: cardioprotection acquired through exercise

David A. Brown and Russell L. Moore

Department of Integrative Physiology, University of Colorado at Boulder, Boulder, Colorado

Emerging evidence indicates that exercise training can provide significant protection against myocardial ischemia-reperfusion injury. In this brief review, we provide a synthesis of current literature in the field and summarize the findings to date. Our intent is to identify the unique elements of cardioprotection acquired by exercise, and to illustrate what distinguishes this physiological acquisition of cardioprotection from all other known types of acquired cardioprotection. Finally, we point to future directions for research in this exciting area.

ischemia; infarction; heart


Address for reprint requests and other correspondence: R. L. Moore, University of Colorado-University of Colorado Regent Administrative Center 306D 26 UCB, Boulder, CO 80309-0354 (e-mail: russell.moore{at}colorado.edu)




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