HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Free Full Text (PDF) Free All Versions of this Article: 103/4/1339    most recent 00181.2007v1 Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (1) Citing Articles via Google Scholar Google Scholar Articles by Zhang, J. Q. Articles by Fretwell, V. S. Search for Related Content PubMed PubMed Citation Articles by Zhang, J. Q. Articles by Fretwell, V. S.

Effect of exercise duration on postprandial hypertriglyceridemia in men with metabolic syndrome

¹Laboratory of Cardiovascular Research, University of Texas at San Antonio, ²Department of Pharmacology, University of Texas Health Science Center at San Antonio, and ³Laboratory of Exercise Biochemistry and Metabolism, University of Texas at San Antonio, San Antonio, Texas

Submitted 12 February 2007 ; accepted in final form 15 July 2007

We examined the effect of exercise on postprandial hypertriglyceridemia (PHTG) and insulin resistance in individuals with metabolic syndrome. Subjects were 10 hypertriglyceridemic men with insulin resistance [age = 35.0 ± 1.8 yr, body weight = 90.7 ± 3.3 kg, fasting triglyceride (TG) = 2.6 ± 0.4 mmol/l, peak oxygen consumption (O_2peak) = 36.0 ± 1.3 ml^–1·kg^–1·min^–1, and homeostatic model assessment of insulin resistance (HOMA-IR)= 3.1 ± 0.3]. Each participant performed a control trial (Ctr; no exercise) and three exercise trials at 60% of their O_2peak for 30 min (30 min-Ex), 45 min (45 min-Ex) and 60 min (60 min-Ex). All subjects had a fat meal in each trial. In the exercise trials, the subject jogged on a treadmill for a designated duration of 12 h before ingestion of a fat meal. Blood samples were taken at 0 h (before the meal) and at 2, 4, 6, and 8 h after the meal. The plasma TG, area score under TG concentration curve over an 8-h period (TG AUC) after the meal, and HOMA-IR were analyzed. The TG AUC scores in both the 45 min-Ex and 60 min-Ex were 31 and 33% lower, respectively, than Ctr (P < 0.02). There were no significant differences in TG AUC scores between the 30 min-Ex and the Ctr (P > 0.05). There were no trial differences in the fasting plasma glucose concentration (P > 0.05). HOMA-IR values in the 30 min-Ex, 45 min-Ex, and 60 min-Ex trials were lower than the Ctr (P < 0.03), but no significant differences were found in HOMA-IR among the exercise trials. The results suggest that for physically inactive individuals with metabolic syndrome, exercising at moderate intensity for 45 min effectively attenuates PHTG while exercise for 30 min is sufficient to improve insulin action.

exercise duration; postprandial; hypertriglyceridemia; insulin resistance

This article has been cited by other articles:

				Y. E. Tsekouras, F. Magkos, Y. Kellas, K. N. Basioukas, S. A. Kavouras, and L. S. Sidossis High-intensity interval aerobic training reduces hepatic very low-density lipoprotein-triglyceride secretion rate in men Am J Physiol Endocrinol Metab, October 1, 2008; 295(4): E851 - E858. [Abstract] [Full Text] [PDF]