Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 102: 564-572, 2007. First published October 12, 2006; doi:10.1152/japplphysiol.00767.2006
8750-7587/07 $8.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
102/2/564    most recent
00767.2006v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (4)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Legerlotz, K.
Right arrow Articles by Niehoff, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Legerlotz, K.
Right arrow Articles by Niehoff, A.

The effect of running, strength, and vibration strength training on the mechanical, morphological, and biochemical properties of the Achilles tendon in rats

Kirsten Legerlotz,1 Peter Schjerling,2,3 Henning Langberg,4 Gert-Peter Brüggemann,1 and Anja Niehoff1

1Institute of Biomechanics and Orthopaedics, German Sport University Cologne, Cologne, Germany; 2Department of Molecular Muscle Biology, Rigshospitalet, 3Department of Medical Biochemistry and Genetics, University of Copenhagen, and 4Institute of Sports Medicine, Bispebjerg Hospital, Copenhagen, Denmark

Submitted 11 July 2006 ; accepted in final form 5 October 2006

Compared with muscle or bone, there is a lack of information about the relationship between tendon adaptation and the applied loading characteristic. The purpose of the present study was to analyze the effect of different exercise modes characterized by very distinct loading patterns on the mechanical, morphological, and biochemical properties of the Achilles tendon. Sixty-four female Sprague-Dawley rats were divided into five groups: nonactive age-matched control (AMC; n = 20), voluntary wheel running (RT; n = 20), vibration strength-trained (LVST; n = 12), high-vibration strength-trained (HVST; n = 6), and high strength-trained (HST; n = 6) group. After a 12-wk-long experimental period, the Achilles tendon was tested mechanically and the cross-sectional area, the soleus and gastrocnemius muscle mass, and mRNA concentration of collagen I, collagen III, tissue inhibitor of metalloproteinase-1 (TIMP-1), transforming growth factor-beta, connective tissue growth factor, and matrix metalloproteinase-2 was determined. Neither in the LVST nor in the HVST group could any adaptation of the Achilles tendon be detected, although the training had an effect on the gastrocnemius muscle mass in the LVST group (P < 0.05). In the HST group, the highest creep was found, but the effect was more pronounced compared with the LVST group (P < 0.05) than with the AMC group. That indicates that this was rather induced by the low muscle mass rather than by training. However, the RT group had a higher TIMP-1 mRNA concentration in the Achilles tendon in contrast to AMC group (P < 0.05), which suggests that this exercise mode may have an influence on tendon adaptation.

failure test; hysteresis; cross-sectional area; tissue inhibitor of metalloproteinase-2


Address for reprint requests and other correspondence: K. Legerlotz, Institute of Biomechanics and Orthopaedics, C. Diem Weg 6, 50933 Cologne, Germany (e-mail: Legerlotz{at}dshs-koeln.de)




This article has been cited by other articles:


Home page
 Exp PhysiolHome page
M. Velders, K. Legerlotz, S. J. Falconer, N. S. Stott, C. D. McMahon, and H. K. Smith
Effect of botulinum toxin A-induced paralysis and exercise training on mechanosensing and signalling gene expression in juvenile rat gastrocnemius muscle
Exp Physiol, December 1, 2008; 93(12): 1273 - 1283.
[Abstract] [Full Text] [PDF]

Home page
 Exp PhysiolHome page
K. Legerlotz, B. Elliott, B. Guillemin, and H. K. Smith
Voluntary resistance running wheel activity pattern and skeletal muscle growth in rats
Exp Physiol, June 1, 2008; 93(6): 754 - 762.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
P. Eliasson, A. Fahlgren, B. Pasternak, and P. Aspenberg
Unloaded rat Achilles tendons continue to grow, but lose viscoelasticity
J Appl Physiol, August 1, 2007; 103(2): 459 - 463.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
K. M. Heinemeier, J. L. Olesen, F. Haddad, H. Langberg, M. Kjaer, K. M. Baldwin, and P. Schjerling
Expression of collagen and related growth factors in rat tendon and skeletal muscle in response to specific contraction types
J. Physiol., August 1, 2007; 582(3): 1303 - 1316.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. Kjaer
Matrix loaded and unloaded: can tendons grow when exercised?
J Appl Physiol, February 1, 2007; 102(2): 515 - 515.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2007 by the American Physiological Society.