Journal of Applied Physiology AJP: Renal Physiology
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J Appl Physiol 10: 297-300, 1957;
8750-7587/57 $5.00
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Quantitative Analysis of a Direct Writing Method for Dye Dilution Curves

Norman E. Shumway 1, John A. Johnson 1, and Richard J. Stish 1

1 From the Department of Physiology, University of Minnesota School of Medicine, Minneapolis, Minnesota

A method for continuous inscription of dye dilution curves was critically analyzed by comparing calculated flow rates with measured flows in a variety of test systems. In the same model system, flows calculated from injection of dye into water tended to be less than measured values, while rates of flow estimated from dye injection into blood were usually greater than known values. All measured flows were determined by stopwatch and calibrated cylinder. Right heart bypass in the dog permitted rigid analysis of the technique under relatively physiological conditions. With accurately measured rates of flow delivered into the pulmonary artery, the mean error of estimated values was less than +5%.

Submitted on May 21, 1956




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